Alphagan Drug Interactions

Generic Alphagan Eye Drop for Glaucoma is a disease that leaves their patients completely blind. It develops when the eye fluid movements start pressuring the eyes. Most of the times, patients can not feel it happening.

To treat this condition, doctors use a drug called Brimonidine Tartrate. In the pharmacies, it is sold under several different names. The most popular of them is Alphagan eye drop. It is a brimonidine tartrate ophthalmic solution.

In medical books, Alphagan ophthalmic solution is called Alpha-2 Adrenergic Receptor Agonist/Topical Intraocular Pressure Lowering Agent. Alphagan decreases the eye pressure by reducing the production of new eye fluid and nurturing the flow of the already existing fluid. Till now, this is the main treatment of Glaucoma.

Patients usually take two doses a day, each after every twelve hours. In some cases, patients have to take up to three dosages every day. It depends on the instruction of the doctor.

The size of an Alphagan eye drop bottle is usually 5 ml.

There are 10 ml and 15 ml bottles, too.

Right now, there are Alphagan P Ophthalmic Solution 0.1% and Alphagan P Ophthalmic Solution 0.15% available in the market. The regular market price starts from $175.50 USD and goes up to to around $542.54 USD, depending on the size of the bottle.

But there are some websites where Alphagan is available in a cheaper price these days. One of them is fairpricerx.

This site is has two Alphagan eye drops. The first one is sold at just $11.91 USD, while the other costs around $164.50 USD.

Drugs Alphagan interact with…

Sometimes, Alphagan ophthalmic solution interacts with other medicines a patient is taking.

It is not always serious. But patients are advised to talk it out with their doctors, to make sure no harm is coming on the way.

There are at least 778 drugs which might have possible interactions with Alphagan ophthalmic solution. Some of them are minor, while others do have the potential of harming the patient.

The critical drugs in this list are:-










·Nitroglycerin Rectal,

·Olmesartan Phenelzine,






·Selegiline Transdermal,


·Tranylcypromine and


It also interacts with Aspirin, Timolol, Tylenol, Antipsychotics, Tricyclic Antidepressants, Narcotic Pain Relievers, Muscle Relaxants and Alcohol. Some examples include Morphine, Clozapine, Imipramine, Haloperidol, Methocarbamol etc.

Altogether, there are three types of diseases which interact with Alphagan. They are Depression, Cardiovascular diseases and Renal/Liver diseases.

Alphagan ophthalmic solution is not always suitable for people who have depression, Raynaud’s phenomenon, orthostatic hypotension, thromboangiitis obliterans etc.

If a medicine is interacting with Alphagan ophthalmic solution, it has to be discussed with the doctor. Patients should also tell the doctor if they are taking a herbal medicine.

The doctor will make the necessary alterations after checking the situation. A medicine might be totally stopped if it is having bad effects. Doctors might change one of the medicines as well.

However, sometimes it is not that much of a big deal and patients can continue taking both medications upon doctor’s clearance.

Patients are always advised to consult their doctors about these issues. The doctor is supposed to tell the patient what to do if a medicine is interacting with Alphagan ophthalmic solution.

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